Head of Statistical Consulting Unit, Ludwig-Maximilians-Universität, Munich
April 2023 - September 2024
Akademische Oberrätin at the Institute of Statistics at the Ludwig-Maximilians-Universität, Munich
October 2021 - March 2023
Interim professor for Biostatistics at the Institute of Statistics at the Ludwig-Maximilians-Universität, Munich
January 2018 - October 2021
Postdoctoral Researcher at the Institute for Medical Information Processing, Biometry and Epidemiology at the Ludwig-Maximilians-Universität, Munich
2017
PhD in Biostatistics, Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France, "A Bayesian hierarchical approach to account for measurement error in the protracted low-dose exposure to ionizing radiation in the estimation of the risk of radiation-induced cancers. Application to a cohort of uranium miners."
2014
Master's degree equivalent in Statistics (Diplôme d'ingénieur), École Nationale de la Statistique et de l'Analyse de l'Information (ENSAI), Rennes, France, Specialisation: Biostatistics
2014
Master's degree in Modeling in clinical pharmacology and epidemiology, Université de Rennes 1, Rennes, France, Specialisation: Epidemiology
Stadlbauer, A., Verbelen, T., Binzenhöfer, L., Goslar, T., Supady, A., Spieth, P. M., ... & Lüsebrink, E. (2025). Management of high-risk acute pulmonary embolism: an emulated target trial analysis. Intensive Care Medicine, 1-16.
Naudet, F., Patel, C., DeVito, N.J., Le Goff, G., Cristea, I.A., Braillon, A., Hoffmann, S. (2024), Can the transparency, reliability and accountability of observational studies be improved through registration?, The BMJ, 384:e076123.
Mandl M, Becker-Pennrich A, Hinske C,Hoffmann, S, Boulesteix AL (2024),Addressing researcher degrees of freedom through minP adjustment, BMC Medical Research Methodology, 24:152.
Vinatier C, Hoffmann S, Patel C, DeVito, NJ, Cristea IA, Tierney B, Ioannidis JPA, Naudet F, (2024) What is the vibration of effects?, BMJ Evidence-Based Medicine.
Boulesteix AL,Hoffmann S, (2024) To adjust or not to adjust: It is not the tests you perform that count, but how you report them, BMJ Medicine, 3:e000783.
Hoffmann, S., Luijken, K., Sauerbrei, W., Shaw, P., Boulesteix, A.L. (2023), STRengthening Analytical Thinking for Observational Studies (STRATOS): Introducing the Open Science Panel, Biometric Bulletin, 40 (2), 8-9.
Rehms, R., Ellenbach, N., Rehfuess, E.A., Burns, J., Mansmann, U.,Hoffmann, S.A Bayesian hierarchical approach to account for reporting uncertainty, variants of concern and vaccination coverage when estimating the effects of non-pharmaceutical interventions on the spread of infectious disease: An application to COVID-19, Biometrical Journal, Conditional acceptance
Khazaei, Y., Küchenhoff, H.,Hoffmann, S., Syliqi, D., Rehms, R.(2023). Using a Bayesian hierarchical approach to study the association between non-pharmaceutical interventions and the spread of Covid-19 in Germany. Sci Rep 13, 18900 (2023). https://doi.org/10.1038/s41598-023-45950-2
Sroczynski, G., Hallsson, L., Mühlberger, N., Jahn, B., Rehms, R.,Hoffmann, S., Crispin, A., Lindoerfer, D., Mansmann, U., Siebert, U. (2023). Long-term Benefits and Harms of Early Colorectal Cancer Screening in German Individuals with Familial Cancer Risk, International Journal of Cancer, https://doi.org/10.1002/ijc.34747.
Klau, S., Schönbrodt, F., Patel, C., Ioannidis, J., Boulesteix, A. L.,Hoffmann, S. (2023). Comparing the vibration of effects due to model, data pre-processing and sampling uncertainty on a large data set in personality psychology. Meta-Psychology, 7, MP.2020.556 https://doi.org/10.15626/MP.2020.2556
Lüsebrink, E., Scherer, C., Binzenhöfer, L.,Hoffmann, S., Höpler, J., Kellnar, A., Thienel, M., Joskowiak, D., Peterss, S., Petzold, T., Deseive, S., Hein, R., Brunnter, S., Kääb, S., Braun, D., Theiss, H., Hausleiter, J., Hagl, C., Massberg, S., Orban, M. (2023). Heparin-induced thrombocytopenia in patients undergoing venoarterial extracorporeal membrane oxygenation, Journal of Clinical Medicine, 12(1), 362.
Lüsebrink, E., Zimmer, S., Schrage, B., Dabboura, S., Majunke, N., Scherer, C., Aksoy, A., Krogmann, A.,Hoffmann, S., Szczanowicz, L., Schmid, T., Mauthe, K., Joskowiak, D., von Samson-Himmelstjerna, P., Peterss, S., Kühn, C., Hagl, C., Massberg, S., Schäfer, A., Thiele, H., Westermann, D., Orban, M. (2022), Intracranial hemorrhage in adult patients on venoarterial extracorporeal membrane oxygenation: A retrospective multicenter study, Eur Heart J Acute Cardiovasc Care, 11(4): 303-311.
Nießl, C.,Hoffmann, S., Ullmann, T., Boulesteix, A.L. (2023). Explaining the performance evaluation of newly proposed methods: A cross-design validation experiment, Biometrical Journal. https://doi.org/10.1002/bimj.202200238
Hiller, T.S., Hoffmann, S., Teismann, T., Lukaschek, K., Gensichen, J. (2023). Psychometric evaluation and Rasch analyses of the German Overall Anxiety Severity and Impairment Scale (OASIS-D). Scientific Reports 13, 6840. https://doi.org/10.1038/s41598-023-33355-0
Hoffmann, S., F. Schönbrodt, R. Elsas, R. Wilson, U. Strasser, Boulesteix, A. L. (2021). The multiplicity of analysis strategies jeopardizes replicability: lessons learned across disciplines. Royal Society Open Science 8 201925
Seibold, H. Boulesteix, A. L., Charleton, A.,Hoffmann, S.(2021). Statisticians roll up your sleeves! There's a crisis to be solved. Significance. 18(4):42-44. https://doi.org/10.1111/1740-9713.01554
Polus, S., Burns, J.,Hoffmann, S., Mathes, T., Mansmann, U., Been, J. V., Lack, N., Koller, D., Maier, W., Rehfuess E. A. (2021). Interrupted time series study found mixed effects of the impact of the Bavarian smoke-free legislation on pregnancy outcomes. Scientific Reports, 11(1) 1-12.
Burns, J., Movsisyan, A., Stratil, J. M., Coenen, M., Emmert-Fees, K. M. F., Geffert, K.,Hoffmann, S., Horstick, O., Klinger, C., Kratzer, S., Laxy, M., Litwin, T., Norris, S., Pfadenhauer, L. M., von Philipsborn, P., Sell, K., Stadelmaier, J., Verboom, B., Voss, S., Wabnitz, K., Rehfuess, E. A. (2021). International travel-related control measures to contain the COVID-19 pandemic: a rapid review. Cochrane Database of Systematic Reviews 2021.
Czermak, T., Hagl, C., Samson-Himmelstjerna, P.N., Sadoni. S., Heyn, O., Hartrampf, B., Lemmermöhle, E., Klier, I., Rehms, R.,Hoffmann, S., Estner, H.L., Massberg, S., Fichtner, S., Lackermair, K. (2021). Survival after left ventricular assist device implantation correlates with a novel device-based measure of heart rate variability: the heart rate score. Interactive cardiovascular and thoracic surgery, 1-7.
Burns, J.,Hoffmann, S., Kurz, C., Laxy, M., Polus, S., Rehfuess, E. (2021). COVID-19 mitigation measures and nitrogen dioxide–A quasi-experimental study of air quality in Munich, Germany. Atmospheric Environment, 246, 118089.
Klau, S. *,Hoffmann, S.,*, Patel, C., Ioannidis, J., Boulesteix, A. L. (2021). Examining the robustness of observational associations to model, measurement and sampling uncertainty with the vibration of effects framework. International Journal of Epidemiology, 50(1) 266-278. *Both authors contributed equally to this work.
Burns, J., Movsisyan, A., Stratil, J. M., Coenen, M., Emmert-Fees, K. M. F., Geffert, K.,Hoffmann, S., Horstick, O., Laxy, M., Pfadenhauer, L. M., von Philipsborn, P., Sell, K., Voss, S., Rehfuess, E. A. (2020). Travel-related control measures to contain the COVID-19 pandemic: a rapid review. Cochrane Database of Systematic Reviews 9.
Boulesteix, A. L.,Hoffmann, S., Charleton, A., Seibold, H. (2020). A replication crisis in methodological research? Significance 17(5), 18-21.
Hoffmann, S., Crispin, A., Lindoerfer, D., Sroczynski, G., Siebert, U., Mansmann, U., & FARKOR Consortium (2020). Evaluating the effects of a risk-adapted screening program for familial colorectal cancer in individuals between 25 and 50 years of age: study protocol for the prospective population-based intervention study FARKOR. BMC gastroenterology 20, 1-9.
Klau, S., Martin‐Magniette, M. L., Boulesteix, A. L.*, &Hoffmann, S.* (2020). Sampling uncertainty versus method uncertainty: A general framework with applications to omics biomarker selection. Biometrical Journal 62(3), 670-687. *Both authors contributed equally to this work.
Boulesteix, A. L., Wright, M. N.,Hoffmann, S., & König, I. R. (2020). Statistical learning approaches in the genetic epidemiology of complex diseases. Human genetics, 139, 73-64.
Durand, T., Berzero G., Bompaire F.,Hoffmann, S., Léger, I., Jego, V., Baruteau, M., Delgadillo, D., Taillia, H., Psimaras, D., & Ricard D. (2018). Episodic Memory Impairments in Primary Brain Tumor Patients. Archives of Clinical Neuropsychology, 33 (8), 949–955.
Hoffmann, S., Guihenneuc, C., & Ancelet, S. (2018). A cautionary comment on the generation of Berkson error in epidemiological studies. Radiation and Environmental Biophysics, 57(2), 189-193.
Hoffmann, S., Laurier, D., Rage, E., Guihenneuc, C., & Ancelet, S. (2018). Shared and unshared exposure measurement error in occupational cohort studies and their effects on statistical inference in proportional hazards models. PloS One, 13(2), e0190792.
Samson, E., Leuraud, K., Rage, E., Caer-Lorho, S., Ancelet, S., Cléro, E., Bouet, S.,Hoffmann, S., Fournier, L., Belloni, M., Jovanovic, I., Bah, T., Davesne, E., Blanchardon, E., Challeton-de Vathaire, C., Laurier, D., Laurent, O. (2018) Bilan de la surveillance épidémiologique des travailleurs du cycle électronucléaire en France. Radioprotection, 53(3), 175-184.
Hoffmann, S., Rage, E., Laurier, D., Laroche, P., Guihenneuc, C., & Ancelet, S. (2017). Accounting for Berkson and classical measurement error in radon exposure using a Bayesian structural approach in the analysis of lung cancer mortality in the French cohort of uranium miners. Radiation Research, 187(2), 196-209.
Hoffmann, S., & Sobotzki, C. (2017). Response to'avoidance of sun exposure as a risk factor for major causes of death: a competing risk analysis of the Melanoma in Southern Sweden cohort'. Journal of internal medicine, 281(6), 622.
Book Chapter: Hoffmann, S., Scheipl, F., Boulesteix, A.L. (2023). Reproduzierbare und replizierbare Forschung. Accepted for inclusion in “Moderne Verfahren der Angewandten Statistik“, Springer